Table 5.
No of studies | OR (95% CI) | P value | χ2/df* | |
---|---|---|---|---|
Diabetes (all studies) | 25 | 9.8 (5.5 to 17.4) | <0.001 | 3.21 |
Method of virus detection: | ||||
RNA | 21 | 8.8 (4.7 to 16.7) | <0.001 | 3.37 |
vp1 | 4 | 15.4 (7.5 to 31.5) | <0.001 | 0.35 |
Case definition: | ||||
Newly diagnosed | 12 | 12.7 (6.4 to 25.2) | <0.001 | 2.44 |
Established (including recent onset) | 11 | 10.8 (4.0 to 29.4) | <0.001 | 2.62 |
Eventual | 2 | 1.3 (0.2 to 6.9) | 0.79 | 1.60 |
Study location: | ||||
Europe only | 19 | 8.6 (4.3 to 17.3) | <0.001 | 3.75 |
Non-European countries | 6 | 13.5 (7.1 to 25.8) | <0.001 | 0.34 |
Study quality: | ||||
NOS score ≥5 | 18 | 9.0 (4.6 to 17.5) | <0.001 | 3.77 |
NOS=Newcastle-Ottawa.
*Cochrane χ2 divided by degrees of freedom. Values >1 indicate heterogeneity.