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. Author manuscript; available in PMC: 2012 Feb 9.
Published in final edited form as: J Am Chem Soc. 2011 Jan 5;133(5):1597–1602. doi: 10.1021/ja110115a

Table 1.

Thio-FCMA mediated Aspartylation.a

graphic file with name nihms-262776-t0006.jpg
entry peptide + glycan
ratio (P:G)		 isonitrile product yield
1 7 + 14
(1.5:1)		 2.0 eq. graphic file with name nihms-262776-t0007.jpg 70%
2 9 + 14
(3:1)		 5.0 eq. graphic file with name nihms-262776-t0008.jpg 59%
3 9 + 15
(3:1)		 5.0 eq. graphic file with name nihms-262776-t0009.jpg 80%
4 13 + 15
(4:1)		 8.0 eq. graphic file with name nihms-262776-t0010.jpg 19%
a

Key. DMSO, 4Å MS, 2–8 eq. cyclohexyl isonitrile.