Table 3.
Testicular Parameters of control and PTU-exposed Akt1+/+, Akt1+/−, and Akt1−/− Mice.
| Postnatal Day and Exposure Group | Akt1+/+ | Akt1+/− | Akt1−/− |
|---|---|---|---|
|
PND15 Control (mg) |
19.8±1.2 N=9 |
17.9±0.9 N=18 |
12.1±0.6a N=4 |
|
PND15 PTU (mg) |
20.5±1.7 N=5 |
17.9±1.3 N=12 |
10.8±1.5b N=4 |
|
PND25 Control (mg) |
58.6 ± 2.0 N=21 |
52.9 ± 2.8 N=20 |
47.0 ± 2.6a N=6 |
|
PND25 PTU (mg) |
58.1 ± 2.9 N=16 |
42.0 ± 3.3b N=14 |
23.6 ± 1.7b,I N=16 |
|
PND90 Control (mg) |
159.7 ± 7.3 N=9 |
164.7 ± 4.9 N=17 |
108.1 ± 9.2a N=6 |
|
PND90 PTU (mg) |
217.8 ± 1.2b N=3 |
197.1 ± 5.2b N=15 |
114.0 ± 18.3 N=3 |
Given values are in mean ± S.D.;
a
denotes statistically different due to genotype effect;
b
denotes statistically different due to PTU exposure effect;
I
denotes statistically significant interaction due to genotype exposure effect.