Table 1.
Gamma-Expiratory | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Slope | Y-intercept | |||||||||||
Control | 1µl IA | 10µl IA | Control | 1µl IA | 10µl IA | |||||||
n−1 | n | n−1 | n | n−1 | n | n−1 | n | n−1 | n | n−1 | n | |
TI | 0.11 (0.06) | * 0.20 (0.05) | 0.14 (0.07) | * 0.29 (0.02) | 0.16 (0.09) | 0.23 (0.07) | 0.93 (0.07) | * 0.66 (0.02) | 0.89 (0.07) | * 0.61 (0.04) | 0.86 (0.08) | * 0.71 (0.05) |
TE | 0.05 (0.01) | * 0.81 (0.06) | 0.07 (0.02) | * 0.90 (0.03) | 0.03 (0.02) | * 0.88 (0.06) | 0.97 (0.01) | * 0.29 (0.06) | 0.96 (0.02) | * 0.23 (0.05) | 0.95 (0.02) | * 0.21 (0.06) |
TTot | 0.07 (0.02) | * 0.63 (0.06) | 0.09 (0.01) | * 0.71 (0.02) | 0.08 (0.02) | * 0.68 (0.05) | 0.95 (0.02) | * 0.40 (0.05) | 0.94 (0.02) | * 0.35 (0.04) | 0.92 (0.03) | * 0.35 (0.04) |
TI/TTot | 0.06 (0.06) | * −0.68 (0.13) | 0.07 (0.08) | * −0.78 (0.12) | 0.15 (0.10) | †* −0.96 (0.15) | 0.97 (0.05) | * 1.50 (0.14) | 0.95 (0.07) | * 1.60 (0.11) | 0.92 (0.08) | †* 1.81 (0.12) |
VT | 0.18 (0.06) | 0.22 (0.07) | 0.21 (0.09) | * 0.34 (0.01) | 0.21 (0.11) | 0.32 (0.10) | 0.85 (0.06) | * 0.66 (0.05) | 0.82 (0.08) | * 0.58 (0.02) | 0.83 (0.10) | * 0.61 (0.07) |
VT/TI | 0.10 (0.02) | 0.06 (0.05) | 0.11 (0.03) | 0.08 (0.04) | 0.08 (0.05) | 0.14 (0.06) | 0.90 (0.01) | * 0.97 (0.07) | 0.89 (0.03) | 0.95 (0.06) | 0.93 (0.05) | † 0.86 (0.07) |
Expiratory gamma analysis. Asterisks denote significant (P < 0.05) difference of n breath from n−1 breath. Daggers denote significant (P < 0.05) difference from respective control value. Shaded cells indicate departures from control study trends due to injection of 1 and/or 10µl of ibotenic acid (IA). TI, inspiratory time; TE, expiratory time; TTot, total respiratory cycle time; TI/TTot, inspiratory drive; VT, tidal volume; VT/TI, volume per inspiration.