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. 2010 Nov 13;376(9753):1647–1657. doi: 10.1016/S0140-6736(10)61924-1

Table 3.

Recovery times in surviving patients according to treatment group

Quinine (median, IQR) N Artesunate (median, IQR) N HR (95% CI) p value
Time to discharge (days) 3·0 (2·0–5·0) 2412 3·0 (2·0–5·0) 2478 1·04 (0·99–1·10) 0·059
Time to eat (h) 12 (2–24) 2269 9 (0–24) 2358 0·99 (0·93–1·06) 0·74
Time to sit unsupported (h) 22 (6–44) 2312 18 (6–42) 2373 1·02 (0·95–1·08) 0·60
Time to localise pain (h)* 12 (6–24) 726 12 (6–24) 698 0·87 (0·78–0·98) 0·0093
Time to speak (h)* 18 (11–36) 695 20 (8–42) 664 0·88 (0·79–0·99) 0·016
*

Time to localise pain and time to speak was assessed only for surviving patients with coma on admission (Blantyre coma scale <3 or Glasgow coma scale <11).