Table 2.
Bivariate correlations between whole blood stimulated IFNγa and anthropometric and biochemical variables in obese and non-obese premenopausal women at baseline
| Obese (n=17 | Non-obese (n=19) | |||
|---|---|---|---|---|
| IFNγ LPS | IFNγ ZY | IFNγ LPS | IFNγ ZY | |
| BMI (kg/m2) | −0.16 | −0.06 | −0.09 | −0.28 |
| Waist Circ. (cm) | −0.17 | −0.09 | −0.07 | −0.38 |
| Serum IL-6 (pg/mL) | −0.14 | 0.18 | −0.23 | −0.31 |
| CRP (mg/L) | −0.13 | 0.13 | 0.11 | 0.21 |
| HOMA-IR | −0.03 | 0.18 | 0.08 | 0.14 |
| Hemoglobin (g/dL) | −0.31 | 0.20 | 0.01 | 0.33 |
| Serum hepcidin (ng/mL) | −0.61b | −0.63b | 0.21 | 0.30 |
| sTfR (nmol/L) | 0.47 | 0.58b | −0.08 | −0.17 |
a
units are in pg/mL
b
p <0.025 (correction factor= 0.05/2 groups)
Abbreviations: BMI, body mass index; IL-6, interleukin-6; CRP, high sensitivity C reactive protein; HOMA-IR, homeostasis model assessment of insulin resistance; sTfR, serum transferring receptor; IFNγ, interferon gamma LPS, lipopolysacchride; ZY, zymosan