Fig. 3.

A, Abundance of the vast majority of proteins is unchanged during aging in mice as indicated by a histogram representation of protein abundance ratios between old and young animals in hippocampus or frontal cortex. B, Pearson correlation between the proteomes of mice within the young or old age groups is not generally higher than between old and young individuals. Correlation coefficients in the matrix are color coded as shown. C, Principal component analysis of the individual proteomes.