TABLE 3.

Summary of modeling parameters from CoMFA analysis

	Vmax Model	CLint Model
q2a	0.738	0.561
SEPb	0.383	0.561
r2c	0.976	0.938
rpredd	0.735	0.630
S.E.e	0.116	0.229
Componentsf	6	4
Fg	108.836	68.436
Pr2 = 0h	0.000	0.000
Fraction
Steric	0.395	0.450
Electrostatic	0.605	0.550

^a Cross-validated correlation coefficient after the leave-one-out procedure.

^b Cross-validated standard error of prediction.

^c Non-cross-validated correlation coefficient.

^d Correlation coefficient for test set predictions.

^e Standard error of estimate.

^f Optimum number of components.

^g F-test value.

^h Probability of obtaining the observed F ratio value by chance alone.