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[14C]sucrose-corrected uptake of [3H]nifurtimox in selected brain regions of FVB-Mdr1a/1b(+/+) (wild type) compared with FVB-Mdr1a/1b(−/−) (P-gp deficient) mice. Perfusion time was 10 min. Each data point shows n = 4–6. Data are not shown for caudate putamen, hippocampus and CVOs (choroid plexuses, pituitary gland, and pineal gland).
