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. Author manuscript; available in PMC: 2011 Feb 4.
Published in final edited form as: Mol Immunol. 2008 Oct 17;46(4):677–687. doi: 10.1016/j.molimm.2008.08.281

Figure 5.

Figure 5

Inhibition of GSK3β confers a survival advantage in mice infected with F. tularensis LVS. C57BL/6 wt mice were immunized (i.p.) with different doses of F. tularensis LVS in 500 μl of PBS. For GSK3β inhibition, LiCl was given i.p. at 100 μg/g body weight 1 h before (LiCl + LVS) or after (LVS + LiCl) F. tularensis LVS infection. Mice were monitored daily over a 14-day period for survival. Results are expressed as Kaplan-Meier curves and P values were determined using a log rank test. The results show pooled data of three independent experiments (a total of 15 mice/group).