Table 1.
Association of γ' Fibrinogen with Traditional Cardiovascular Risk Factors.a
| Factor | γ' Fibrinogen Tertiles | P-Valueb | ||
|---|---|---|---|---|
| | ||||
| Low (0.03655 - 0.19827) (N=1099) | Mid (0.19831 - 0.28564) (N=1100) | High (0.28567 - 1.44290) (N=1100) | ||
| Age (years) | 58.8 (± 9.0) | 60.9 (± 9.6) | 63.5 (± 9.3) | <0.001 |
| Female (%) | 50.3 | 54.7 | 55.5 | 0.023 |
| Body mass index (kg/m2) | 27.5 (± 4.9) | 28.1 (± 5.4) | 28.9 (± 5.6) | <0.001 |
| Cigarette smoking (%) | 13.4 | 11.8 | 14.2 | 0.019 |
| Diabetes mellitus (%) | 10.3 | 11.8 | 17.8 | <0.001 |
| Fasting blood glucose (mmol/L) | 5.69 (± 1.50) | 5.69 (± 1.24) | 6.00 (± 1.74) | <0.001 |
| Systolic blood pressure (mm Hg) | 125.0 (± 18.1) | 126.7 (± 18.2) | 129.5 (± 19.7) | 0.223 |
| Total cholesterol (mmol/L) | 5.23 (± 0.92) | 5.19 (± 0.95) | 5.14 (± 0.98) | 0.112 |
| HDL cholesterol (mmol/L) | 1.44 (± 0.45) | 1.40 (± 0.44) | 1.33 (± 0.43) | <0.001 |
| Triglycerides (mmol/L) | 1.49 (± 0.98) | 1.50 (± 0.96) | 1.66 (± 1.05) | <0.001 |
| Total fibrinogen (g/L) | 3.422 (±0.60) | 3.754 (±0.60) | 4.226 (±0.80) | <0.001 |
| γ' fibrinogen (g/L) | 0.15 (± 0.04) | 0.24 (± 0.02) | 0.39 (± 0.11) | - |
a
Results are unadjusted mean (±1 standard deviation) or %.
b
P-values assess the significance of the difference in mean/% across fibrinogen tertiles and are age and sex-adjusted (P-value for age is sex-adjusted only, and P-value for sex is age-adjusted only).