Table 2.
Tumor and patient characteristics of the 67 tumors used for MSI and array CGH analysis.
| ID | gender | age | Tumor type | T | N | origin | MSI status | Cluster number | Cluster order | % events | % gains | % losses |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 62 | intestinal | T2 | N1 | Cauc SA | MSS | 5 | 34 | 3.2 | 3.2 | 0 |
| 2 | M | 73 | intestinal | T2 | N2 | Cauc SA | MSS | 5 | 28 | 16.9 | 13.4 | 3.4 |
| 3 | F | 59 | intestinal | T2 | N1 | Cauc SA | MSS | 5 | 26 | 26.5 | 15.1 | 11.4 |
| 4 | F | 74 | intestinal | T2 | N1 | Cauc SA | MSS | 5 | 27 | 15.7 | 9.3 | 6.5 |
| 5 | M | 56 | intestinal | T3 | N1 | Cauc SA | MSI | - | - | 15.6 | 10.3 | 5.3 |
| 6 | M | 57 | intestinal | T2 | N1 | Cauc SA | MSS | 6 | 48 | 3.4 | 2.4 | 1.0 |
| 7 | F | 84 | intestinal | T1 | N0 | Cauc SA | MSS | 6 | 43 | 10.9 | 7.9 | 3.1 |
| 8 | F | 79 | intestinal | T3 | N0 | Cauc SA | MSI | - | - | 17.6 | 16.8 | 0.8 |
| 9 | M | 68 | intestinal | T3 | N2 | Cauc SA | MSS | 5 | 25 | 32.1 | 24.3 | 7.7 |
| 10 | M | 65 | intestinal | T2 | N0 | native SA | MSI | - | - | 1.7 | 1.7 | 0 |
| 11 | M | 57 | intestinal | T1 | N0 | native SA | MSI | - | - | 0 | 0 | 0 |
| 12 | F | 29 | intestinal | T4 | N0 | native SA | MSS | 6 | 37 | 28.3 | 26.2 | 2.1 |
| 13 | F | 59 | intestinal | T3 | N1 | native SA | MSS | 6 | 42 | 10.6 | 5.3 | 5.3 |
| 14 | M | 66 | intestinal | T2 | N1 | native SA | MSS | 5 | 31 | 6.4 | 6.4 | 0 |
| 15 | M | 46 | intestinal | T3 | N2 | native SA | MSS | 5 | 35 | 3.2 | 3.2 | 0 |
| 16 | F | - | diffuse | T4 | N2 | native SA | MSS | 6 | 44 | 13.2 | 12.4 | 0.7 |
| 17 | M | 51 | intestinal | T3 | N1 | native SA | MSS | 5 | 32 | 6.1 | 6.1 | 0 |
| 18 | F | 49 | intestinal | T3 | N1 | native SA | MSS | 4 | 20 | 29.1 | 18.2 | 10.9 |
| 19 | M | 56 | intestinal | T3 | N1 | native SA | MSS | 4 | 19 | 26.0 | 10.3 | 15.7 |
| 20 | M | 48 | intestinal | T3 | N2 | native SA | MSS | 5 | 36 | 5.4 | 5.4 | 0 |
| 21 | M | 65 | mixed | T3 | N1 | native SA | MSI | - | - | 18.2 | 16.3 | 1.9 |
| 22 | M | 60 | intestinal | T2 | - | native SA | MSS | 6 | 41 | 14.0 | 11.3 | 2.7 |
| 23 | F | 63 | intestinal | - | - | native SA | MSS | 6 | 38 | 17.1 | 10.7 | 6.4 |
| 24 | F | 54 | papillary | T2 | N0 | native SA | MSS | 3 | 14 | 44.8 | 20.6 | 24.2 |
| 25 | M | 67 | intestinal | T3 | N1 | native SA | MSS | - | - | - | - | - |
| 26 | M | 31 | intestinal | T3 | N1 | native SA | MSS | 5 | 24 | 41.1 | 28.4 | 12.7 |
| 27 | M | 43 | intestinal | T3 | N1 | native SA | MSI | - | - | 9.9 | 9.9 | 0 |
| 28 | F | 71 | intestinal | T3 | - | native SA | MSS | 5 | 33 | 3.7 | 2.7 | 1.0 |
| 29 | F | 77 | intestinal | T3 | N1 | native SA | MSS | 5 | 30 | 12.7 | 7.1 | 5.5 |
| 30 | M | 57 | intestinal | T2 | N0 | native SA | MSS | - | - | - | - | - |
| 31 | M | 79 | intestinal | T3 | N2 | native SA | MSI | - | - | 2.5 | 2.5 | 0 |
| 32 | M | 57 | intestinal | T4 | N0 | native SA | MSI | - | - | 17.8 | 16.8 | 1.0 |
| 33 | M | 56 | mixed | T3 | N1 | native SA | MSS | 4 | 17 | 42.2 | 21.3 | 20.9 |
| 34 | F | 49 | mixed | T3 | N3 | native SA | MSS | 5 | 29 | 22.3 | 19.2 | 3.2 |
| 35 | F | 82 | diffuse | T1 | N0 | UK | MSS | 6 | 46 | 11.2 | 10.3 | 1.0 |
| 36 | M | 81 | diffuse | T3 | N2 | UK | MSS | 4 | 22 | 15.7 | 7.2 | 8.5 |
| 37 | M | 71 | diffuse | T2 | N1 | UK | MSS | 7 | 53 | 18.4 | 14.7 | 3.7 |
| 38 | M | 73 | intestinal | T2 | N0 | UK | MSS | 2 | 11 | 26.0 | 17.2 | 8.8 |
| 39 | F | 65 | diffuse | T2 | N3 | UK | MSS | 6 | 45 | 15.0 | 12.0 | 3.1 |
| 40 | F | 58 | diffuse | T3 | N3 | UK | MSS | 1 | 6 | 25.7 | 13.7 | 12.0 |
| 41 | F | 51 | diffuse | T3 | N3 | UK | MSS | 1 | 7 | 22.4 | 16.5 | 6.0 |
| 42 | M | 91 | intestinal | T1 | N0 | UK | MSS | 7 | 56 | 49.2 | 27.6 | 21.6 |
| 43 | M | 71 | diffuse | T3 | N2 | UK | MSS | 7 | 49 | 40.6 | 19.8 | 20.8 |
| 44 | M | 73 | intestinal | T2 | N1 | UK | MSS | 1 | 5 | 21.0 | 8.2 | 12.9 |
| 45 | M | 64 | diffuse | T2 | N0 | UK | MSS | 7 | 50 | 14.9 | 10.3 | 4.6 |
| 46 | F | 71 | intestinal | T1 | N0 | UK | MSS | 1 | 4 | 40.8 | 13.4 | 27.4 |
| 47 | F | 60 | intestinal | T4 | N1 | UK | MSS | 3 | 16 | 30.1 | 15.6 | 14.5 |
| 48 | F | 96 | diffuse | T3 | N0 | UK | MSS | 2 | 12 | 41.0 | 25.0 | 16.0 |
| 49 | M | 91 | mixed | T3 | N0 | UK | MSS | 6 | 40 | 16.0 | 11.4 | 4.6 |
| 50 | M | 81 | diffuse | T2 | N0 | UK | MSS | 2 | 10 | 37.7 | 17.2 | 20.4 |
| 51 | F | 83 | intestinal | T2 | N0 | UK | MSS | 7 | 51 | 14.5 | 10.5 | 4.0 |
| 52 | F | 82 | intestinal | T3 | N1 | UK | MSS | 6 | 47 | 2.2 | 2.2 | 0 |
| 53 | F | 77 | intestinal | T3 | N1 | UK | MSS | 6 | 39 | 19.5 | 11.1 | 8.5 |
| 54 | M | 74 | mixed | T2 | N1 | UK | MSS | 2 | 8 | 44.8 | 22.4 | 22.3 |
| 55 | F | 59 | diffuse | T3 | N1 | UK | MSS | 3 | 15 | 26.4 | 18.1 | 8.2 |
| 56 | M | 77 | mixed | T3 | N2 | UK | MSS | 1 | 3 | 24.1 | 13.7 | 10.3 |
| 57 | M | 75 | intestinal | T2 | N0 | UK | MSS | 2 | 9 | 36.9 | 18.2 | 18.7 |
| 58 | M | 64 | diffuse | T3 | N3 | UK | MSS | 2 | 13 | 35.3 | 20.2 | 15.1 |
| 59 | M | 71 | intestinal | T3 | N1 | UK | MSS | 1 | 2 | 31.0 | 11.7 | 19.3 |
| 60 | F | 74 | diffuse | T3 | N2 | UK | MSS | 4 | 23 | 23.2 | 14.7 | 8.4 |
| 61 | M | 81 | intestinal | T2 | N0 | UK | MSI | - | - | 10.7 | 8.7 | 2.0 |
| 62 | F | 74 | mixed | T3 | N2 | UK | MSS | 4 | 18 | 30.4 | 17.9 | 12.5 |
| 63 | M | 67 | mixed | T3 | N1 | UK | MSS | 7 | 52 | 12.3 | 6.4 | 5.9 |
| 64 | M | 73 | intestinal | T3 | N1 | UK | MSS | 4 | 21 | 15.2 | 7.3 | 7.9 |
| 65 | F | 66 | mixed | T3 | N2 | UK | MSS | 7 | 55 | 34.3 | 18.7 | 15.6 |
| 66 | M | 82 | intestinal | T1 | N1 | UK | MSS | 7 | 54 | 46.7 | 27.4 | 19.3 |
| 67 | F | 62 | mixed | T3 | N0 | UK | MSS | 1 | 1 | 44.0 | 20.7 | 23.3 |
Percentages of events, gains and losses are given for all tumors of sufficient array CGH quality. Cluster number and order are listed for the 56 cases included in the cluster analysis.
F: female, M: male, T: T-stage, N: N-stage MSS: microsatellite stable, MSI: microsatellite instable, Cauc SA: Caucasian South African patients, native SA: native South African patients, UK: patients from United Kingdom, -: unknown.