Table 3.
Detailed overview of frequent DNA copy number aberrations (>30%) of tumors from UK patients.
| chromosomal aberrations | flanking clones | position (bp) | segment size | |||
|---|---|---|---|---|---|---|
| gains | losses | start | end | start | end | (Mb) |
| 1p36.33-p36.21 | RP11-206L10 | RP4-636F13 | 672780 | 12417597 | 11.74 | |
| 1p31.1 | RP5-944F13 | RP11-246O4 | 69815162 | 83112098 | 13.30 | |
| 1p21.3-p13.3 | RP11-146P11 | RP5-1077K16 | 95695632 | 107389118 | 11.69 | |
| 1q21.2-q23.1 | RP4-790G17 | RP11-214H6 | 146971278 | 153444622 | 6.47 | |
| 1q31.1-q31.3 | RP11-134C1 | RP11-75C23 | 184717073 | 194242465 | 9.53 | |
| 1q32.1-q32.2 | RP11-150l7 | RP11-564A8 | 197877387 | 203602276 | 5.72 | |
| 3p26.3 | RP11-385A18 | RP11-129K1 | 46140 | 2377366 | 2.33 | |
| 3p25.1-p24.1 | RP11-255O19 | RP11-99M10 | 15780361 | 30799547 | 15.02 | |
| 3p14.2 | RP11-170K19 | RP11-114P15 | 59701329 | 62639806 | 2.94 | |
| 3p12.3-p11.2 | RP11-103P13 | RP11-91M15 | 75146113 | 96627928 | 21.48 | |
| 4p16.1-q35.2 | RP11-61G19 | CTC-963K6 | 10275012 | 191158370 | 180.88 | |
| 5p15.33 | RP11-811I15 | CTD-2265D9 | 70262 | 2671745 | 2.60 | |
| 5q11.1-q23.3 | RP11-269M20 | RP11-114H7 | 49913067 | 130460728 | 80.55 | |
| 6p21.32-p21.1 | RP11-79I1 | RP11-121G20 | 33123932 | 44385866 | 11.26 | |
| 7p22.3-p22.1 | RP11-713A20 | RP11-161C7 | 106471 | 6396697 | 6.29 | |
| 7p11.2 | RP11-449G3 | RP11-34J24 | 54413814 | 55403627 | 0.99 | |
| 7q22.1 | RP11-10D8 | RP11-163M5 | 98067793 | 101528379 | 3.46 | |
| 7q36.1 | RP11-89P11 | RP11-43l19 | 147485335 | 151131938 | 3.65 | |
| 7q36.3 | RP11-58F7 | RP11-120H14 | 157072238 | 158524109 | 1.45 | |
| 8q24.12-q24.3 | RP11-22A24 | RP5-1109M23 | 120711365 | 146238749 | 25.53 | |
| 9p24.3-p21.1 | RP11-48M17 | RP11-141J7 | 2136329 | 32469400 | 30.33 | |
| 9q33.3-q34.3 | RP11-205K6 | RP11-424E7 | 126296075 | 138363252 | 12.07 | |
| 10p15.3 | RP11-631M21 | RP11-74N14 | 50000 | 1789100 | 1.74 | |
| 10p15.2 | RP11-195B3 | 3293007 | 3338470 | 0.05 | ||
| 10q22.1 | RP11-91A1 | RP11-28E3 | 72033907 | 73573433 | 1.54 | |
| 11p15.5-p15.4 | CTC-908H22 | RP11-304P12 | 178227 | 3140168 | 2.96 | |
| 11q12.2-q13.5 | RP11-286N22 | RP11-30J7 | 60851860 | 76232373 | 15.38 | |
| 12q21.2-q22 | RP1-97G4 | RP11-2K12 | 76228586 | 91346299 | 15.12 | |
| 13q11-q12.11 | RP11-94A1 | RP11-61K9 | 18360157 | 19386914 | 1.03 | |
| 13q21.2-q21.33 | RP11-310K10 | RP11-451E2A | 60721181 | 71574154 | 10.85 | |
| 13q32.3 | RP11-19J14 | RP11-113F15 | 97851594 | 99328275 | 1.48 | |
| 13q33.3-q34 | RP11-61I17 | RP11-569D9 | 108847725 | 114103243 | 5.26 | |
| 14q12 | RP11-330O19 | RP11-109D12 | 25538832 | 26345513 | 0.81 | |
| 14q21.1-q21.3 | RP11-88D14 | RP11-94K16 | 36949212 | 48298851 | 11.35 | |
| 14q31.1-q31.3 | RP11-46l17 | RP11-88N20 | 78630860 | 86772926 | 8.14 | |
| 14q32.31-q32.33 | RP11-367F11 | RP11-815P21 | 101467534 | 105159201 | 3.69 | |
| 15q14 | RP11-294M6 | RP11-79A5 | 33841939 | 35953471 | 2.11 | |
| 16p13.3 | CTD-2148K8 | RP11-89M4 | 87754 | 4697230 | 4.61 | |
| 16p13.2-p13.11 | RP11-475D10 | RP11-489O1 | 8598165 | 15572359 | 6.97 | |
| 16p12.1-p11.2 | RP11-142A12 | RP11-18H23 | 26595069 | 31443695 | 4.85 | |
| 16q21-q22.1 | RP11-52B24 | RP11-394B2 | 63708677 | 69365102 | 5.66 | |
| 16q23.3-q24.3 | RP11-483P21 | RP11-566K11 | 82361609 | 88613383 | 6.25 | |
| 17p13.3-p13.1 | RP11-411G7 | RP11-89A15 | 427024 | 8365794 | 7.94 | |
| 17p11.2 | RP11-524F11 | RP1-162E17 | 17343389 | 19251691 | 1.91 | |
| 17q11.2-q21.31 | RP11-138P22 | RP11-374N3 | 23133763 | 41096064 | 17.96 | |
| 17q21.32-q21.33 | RP11-234J24 | RP11-506D12 | 42655422 | 46333070 | 3.68 | |
| 17q22-q23.2 | RP11-143M4 | RP11-139B3 | 47607556 | 51363278 | 3.76 | |
| 17q24.3-q25.3 | RP11-65C22 | RP11-258N23 | 68165339 | 78308832 | 10.14 | |
| 18q11.2-q23 | RP11-5G23 | RP11-396D4 | 21431314 | 71337306 | 49.91 | |
| 19p13.3-q13.43 | RP11-110A24 | GS1-1129C9 | 134914 | 63771717 | 63.64 | |
| 20p13-q13.33 | RP11-530N10 | CTB-81F12 | 9943 | 62393015 | 62.38 | |
| 21q11.2-q22.11 | RP11-72P4 | RP11-41N19 | 13857799 | 30673984 | 16.82 | |
| 22q11.1-q11.21 | RP11-81H21 | RP11-586I18 | 14754982 | 18976359 | 4.22 | |
| 22q12.3-q13.33 | RP11-90I17 | CTB-99K24 | 35686144 | 49397088 | 13.71 | |