TABLE 2.
Mean levels of suppression of virus replication in L929 cells pretreated with IFN-α/β
| Virus strain | Pretreatment with IFN-α/βa (U/ml) | Log10 reduction in virus titer compared to untreated controls atb:
|
||
|---|---|---|---|---|
| 8 h | 24 h | 48 h | ||
| ZPC738 | 25 | 2.0 | 4.3 | 3.9 |
| SH3 | 2.6 | 3.6 | 3.0 | |
| 3908 | 1.2 | 3.4 | 3.6 | |
| TC-83 | 3.4 | 6.2 | 4.5 | |
| ZPC738 | 50 | 2.0 | 4.8 | 4.2 |
| SH3 | 2.4 | 4.1 | 3.2 | |
| 3908 | 2.9 | 3.2 | 3.8 | |
| TC-83 | 3.8 | 6.2 | 6.3 | |
| ZPC738 | 100 | 2.1 | 5.4 | 4.4 |
| SH3 | 2.4 | 5.2 | 3.6 | |
| 3908 | 1.3 | 3.9 | 4.3 | |
| TC-83 | 4.3 | 6.2 | 6.3 | |
a
That is, pretreatment 24 h prior to infection.
b
Time postinfection with 1,000 PFU of virus.