Table 5.
Multivariate Cox Proportional Hazards Model for Independent Predictors of BOS
Variable | Hazard Ratio | 95% Confidence Interval | p Valuea |
---|---|---|---|
High Pao2 (≥ 75th percentile or ≥ 509 mm Hg) | 1.38 | 1.11-1.73 | 0.005a |
Donor old age (≥ 60 years old) | 1.16 | 1.002-1.33 | 0.047a |
Donor history of myocardial infarction | 1.79 | 1.00-3.19 | 0.05 |
Donor active pulmonary infection | 1.04 | 0.88-1.23 | 0.63 |
Donor traumatic cause of death | 1.0 | 0.87-1.14 | 0.97 |
HLA mismatch | 1.08 | 0.98-1.18 | 0.14 |
Current tobacco use (< 6 months from donation) | 1.33 | 1.18-1.49 | <0.0001a |
Significance p < 0.05
BOS = bronchiolitis obliterans syndrome; HLA = human leukocyte antigens; Pao2 = partial pressure of oxygen in arterial blood.