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. 2011 Feb 4;6(2):e16806. doi: 10.1371/journal.pone.0016806

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) A representative case showing the presence of anti-HLA class I antibodies and the absence of anti-HLA class II antibodies in maternal serum with FlowPRA®-I and -II screening tests, followed by flow cytometry. (B) Spontaneous preterm birth cases have a higher maternal anti-HLA class I seropositivity than normal term birth cases (p<0.01). TB, normal term birth; sPTB, spontaneous preterm birth.