FIG. 1.

PrPc expression in neuroglial cell clones. Six clones derived from DRG of ovine PrP transgenic mice (Table 1) were analyzed for PrPc with 4F2 antibody. A Western blot performed on lysates from cultures at 11 to 15 passages postexplantation of the indicated clones and from primary glial cell cultures of C57BL6 (wild type [wt]) or PrP^0/0 (0/0) mice is shown (10 μg of protein/lane, equivalent to 3 × 10⁴ cells). Molecular masses (in kilodaltons) are indicated to the right of the blot.