Figure 2. Overview of gene expression comparison of Sod2^-/- vs. Sod2^+/+ erythroblasts.

Scatterplot highlights genes expressed >1.5 fold higher (red) or lower (green) in Sod2^-/- compared to Sod2^+/+ cells. X and Y axes plot relative expression values derived from microarray intensities. Spots corresponding to selected highly differentially expressed genes are identified. Among the most highly expressed genes are the hemoglobin alpha and beta chains, that show no difference between Sod2^-/- and Sod2^+/+ samples. In Sod2^-/- erythroblasts, there are more than twice as many transcripts with reduced vs. increased expression. A full listing of differential transcripts (with corrected p<0.05 and fold-change >±1.5) is in table S1.