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. Author manuscript; available in PMC: 2011 Feb 5.
Published in final edited form as: J Pharm Biomed Anal. 2009 Jul 7;50(5):959–965. doi: 10.1016/j.jpba.2009.06.051

Figure 4.

Figure 4

Infusion experiment for matrix effect. Blank plasma extract (50 μL) was injected onto the LC column while a mixture of ARM, DHA, and I.S. (1 μg/mL each in 50% MeCN) was infused into the MS fraction of LC eluate via a “T” connector at a rate of 10 μL/min (gray line). A 50 μL aliquot of 50% MeCN containing 1 μg/mL ARM, DHA, and I.S. was also injected as a control (black line).