Table 3.

Intra-day and inter-day precision (%RSD) and accuracy (% dev) for analysis of artemether and dihydroartemisinin in human plasma.

		Intra-day				Inter-day
	Nominal, ng/mL	2	6	80	170	2	6	80	170
ARM	mean, ng/mL	1.8-2.3	5.2-6.4	70.5-86.8	160-182	1.96	5.98	76.8	170
	SD	0.1-0.2	0.5-0.6	4.0-8.7	4.7-14.2	0.22	0.63	7.7	13
	RSD,%	5.2-8.0	2.9-12	2.0-7.7	2.9-7.9	11	10	10	7.5
	%dev	−11-13	−13-7.1	−12-9.1	−5.8-6.8	−2.1	−0.3	−4.0	0.1
	n	5	5(4)	5	5	25	24	25	25
DHA	mean, ng/mL	1.9-2.1	5.2-5.7	72.5-79.9	152-165	2.00	5.42	74.9	158.2
	SD	0.1-0.1	0.1-0.3	1.8-4.6	4.0-13	0.11	0.27	3.8	8.4
	RSD,%	2.1-5.8	1.8-5.7	1.9-6.0	2.5-8.2	5.3	5.0	5.1	5.3
	%dev	−3.3-5.6	−13- −4.8	−9.3- −0.1	−10- −3.2	0.1	−9.7	−6.4	−6.9
	n	5	5	5	5	25	25	25	25