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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Pharmacol Biochem Behav. 2010 Dec 8;98(1):21–27. doi: 10.1016/j.pbb.2010.12.002

Figure 1.

Figure 1

Diazepam and Δ9-THC reduce marble burying behavior. Mice were injected (i.p.) with diazepam (DZ), THC, or vehicle and tested for anxiety-like behavior in the marble burying assay. Locomotor activity was simultaneously recorded and was quantified as seconds per minute spent immobile. (A,C) Diazepam and THC dose-dependently reduced marble burying. (B,D) Both diazepam and THC also caused sedation at higher doses than required to reduce marble burying. Data are presented as the mean ± SEM (n = 8-11). * p < 0.05, ** p < 0.01 vs. vehicle.