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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Pharmacol Biochem Behav. 2010 Dec 8;98(1):21–27. doi: 10.1016/j.pbb.2010.12.002

Figure 2.

Figure 2

Endocannabinoids reduce marble burying behavior. Mice were injected (i.p.) with the FAAH inhibitor PF-3845, the MAGL inhibitor JZL184, or vehicle and tested in the marble burying assay. Locomotor activity was simultaneously recorded and was quantified as seconds per minute immobile. (A) FAAH dose-dependently reduced marble burying, but (B) had no effect on immobility. (C) JZL184 dose-dependently reduced marble burying, although (D) caused a statistically significant increase in immobility at 40 mg/kg. Data are presented as the mean ± SEM (n = 8). * p < 0.05, ** p < 0.01 vs. vehicle.