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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Org Chem. 2010 Oct 18;75(22):7651–7658. doi: 10.1021/jo1014646

TABLE 8.

The Solvation of Reactants and Complex in the 1:1 Hydrogen-Bonding of 2,2,2-Trifluoroethanol and Propanone

Log L
Solvent Log K Log Ks/Kg TFE Propanone Reactants Complex
gas phase 1.72 0.00 0.00 0.00 0.00 0.00
cyclohexane 1.21 −0.51 1.40 1.86 3.26 2.75
hexane 0.99 −0.58 1.49 1.92 3.41 2.83
CCl4 0.98 −0.74 1.85 2.34 4.19 3.45
benzene 1.00 −0.74 2.28 2.62 4.90 4.16
chlorobenzene 0.82 −0.90 2.23 2.64 4.87 3.97
bromobenzene 0.80 −0.92 2.17 2.62 4.79 3.87
dichloromethane 0.41 −1.31 2.73 3.20 5.93 4.62
trichloromethane 0.22 −1.50 2.65 3.26 5.91 4.41
benzonitrile 0.16 −1.56 3.30 2.85 6.15 4.59
octanol 0.10 −1.62 3.53 2.31 5.84 4.22
water −0.19 −1.91 3.50 2.95 6.45 4.54