A voxel-by-voxel whole brain ANOVA was used to compute F-statistical maps for the main effect of restraint (top panel), the main effect of preload (middle panel), and the restraint by preload interaction (bottom panel). Statistical images thresholded at p < 0.05, corrected for False Discovery Rate with a minimum extent threshold (k) = 5 contiguous voxels, were superimposed on a fiducial cortical rendering of the left and right cortical surfaces (Van Essen et al., 2001).