Figure 3.
AMPA receptor-mediated responses from hippocampal pyramidal neurons show no resensitization. (A) Typical traces recorded from acutely isolated hippocampal neurons from wild-type (+/+) and (B) stargazer mice (stg/stg). Responses are blocked by a selective AMPA receptor antagonist, GYKI 53784 (20 µM). (C) Resensitization percentages from wild type and stargazer acutely isolated hippocampal neurons. (D) Kainate- to glutamate-evoked current ratios in wild type and stargazer are similar. Summary data are mean ± S.E.M.