FIGURE 3.
Patients with impaired cognition and findings of Alzheimer disease (AD) only have more neurofibrillary tangles (combined counts from superior and middle temporal gyri, middle frontal gyrus, inferior parietal lobule, and occipital lobe including the primary visual area) than cohorts with similar levels of cognitive function and concurrent non-AD pathologic findings (Group II). Patients are grouped according to MMSE scores. Blue bars represent Group I no Lewy bodies (LBs), argyrophilic grains (AGs), infarct(s), hippocampal sclerosis (HS), or frontotemporal dementia (FTD). The red bars and yellow bars refer to all Group II cases with cortical LBs or infarct(s), respectively. Results of 2-tailed, 2-sample Student t-test: *, p < 0.05; **, p < 0.001.