Fig. 2.
Summaries of the effects of intravesical infusion of Krebs solution and oxo-M on the average amplitude of phasic bladder contractions (A) and pelvic afferent nerve firing (B, C, D). A: oxo-M (n = 16) did not change peak contraction pressure, but enhanced pelvic afferent nerve firing (25 µM, p < 0.05, n = 16; 50 µM, p < 0.05, n = 16) (B). C: The oxo-M enhancement of afferent nerve firing could be repeated when oxo-M was administered at 40 min intervals (n = 4) and was blocked by AMN (5 µM) (n = 5) (D). * represents P < 0.05, ** represents P < 0.01. Data in A and B are from the same experiments. Data in C and D are from different experiments.