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. Author manuscript; available in PMC: 2012 Jan 15.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Dec 4;21(2):730–733. doi: 10.1016/j.bmcl.2010.11.117

Fig. 2.

Fig. 2

Inhibition and binding of estramustine phosphate to Shp2. (A) IC50 curve of Shp2 PTP inhibition by estramustine phosphate (EMP). (B) Inhibitor kinetics analysis of EMP on the Shp2 PTP. (C) Surface plasmon resonance assay of EMP binding to Shp2. A representative sensorgram and the associated curve fit are shown.