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. Author manuscript; available in PMC: 2012 Jan 25.
Published in final edited form as: Eur J Pharmacol. 2011 Jan 25;651(1-3):96–105. doi: 10.1016/j.ejphar.2010.10.085

Fig. 5.

Fig. 5

To evaluate agonism in the [35S]GTPγS binding assay, the effects of various concentrations of O-2050 alone were tested (top panel). To evaluate antagonism, O-2050 concentrations were tested in combination with 1000nM CP55,940 (bottom panel) in the assay. [35S]GTPγS binding was conducted in membranes prepared from rat cerebellum.