Table 1.

Comparison of PTEN levels in dermal fibroblasts between normal and scleroderma skin

	Age	Sex	Race	Disease duration	TSS	The levels of PTEN in dermal fibroblasts
NS 352	37	F	AA			+++
SSc 351	38	F	AA	2y	3	+
NS 356	60	F	C			++
S5c 355	63	F	C	4M	37	+/−
NS 360	40	F	AA			+
SSc 359	42	F	AA	3y	15	+/−
NS 362	44	F	AA			+/−
SSc 361	49	F	AA	4y	24	+/−
NS 364	54	M	C			++
SSc 363	50	M	C	1.5y	3	+
NS 366	48	M	C			+++
SSc 365	42	M	C	2y	ND	−
NS 368	45	F	C			+
SSc 367	50	F	C	13y	34	−

(−) - none or little staining in < 10% of cells

(−/+) - faint, partial staining in > 20% of cells

(+) - moderate, complete staining in > 20% of cells

(++) – moderate to strong staining in > 50% of cells

(+++) – strong staining in > 50%