Table 1.
Description of the study participants, by post-diagnosis BMI (N = 388)1
| Characteristic | All (n = 388) | BMI < 25 (n = 203) | BMI ≥ 25 (n = 185) | p† |
|---|---|---|---|---|
| Age at diagnosis (years), mean ± SD | 58.55 ± 10.81 | 59.20 ± 11.46 | 57.84 ± 10.03 | 0.218 |
| Time since diagnosis (months), mean ± SD | 9.28 ± 8.68 | 8.67 ± 7.96 | 9.95 ± 9.38 | 0.145 |
| Weight (lbs), mean ± SD | 153.08 ± 35.73 | 129.17 ± 14.65 | 179.32 ± 34.71 | <0.0001 |
| BMI, mean ± SD | 26.17 ± 5.82 | 22.02 ± 1.90 | 30.73 ± 5.23 | <0.0001 |
| SEER2 Stage, n (%) | 0.279 | |||
| 1 | 64 (16.80) | 35 (20.96) | 29 (15.76) | |
| 2 | 79 (20.73) | 38 (22.75) | 41 (22.28) | |
| 3+ | 238 (62.47) | 124 (74.25) | 114 (61.96) | |
| Known Chemotherapy Treatment, n (%) | 300 (77.32) | 157 (77.34) | 143 (77.30) | 0.575 |
| Tumor Histology, n (%) | 0.799 | |||
| Invasive Serous | 250 (64.43) | 132 (65.02) | 118 (63.78) | |
| Invasive Non-serous | 138 (35.57) | 71 (34.98) | 67 (36.22) | |
| Race, n (%) | 0.771 | |||
| White | 368 (96.08) | 194 (96.52) | 174 (95.60) | |
| Other | 15 (3.92) | 7 (3.48) | 8 (4.40) | |
| Education ≥ 12 yrs, n (%) | 349 (89.95) | 186 (91.63) | 163 (88.11) | 0.250 |
| Age at Menarche, mean ± SD | 12.68 ± 1.50 | 12.79 ± 1.38 | 2.55 ± 1.62 | 0.122 |
| Parity, n (%) | 308 (79.38) | 159 (78.33) | 149 (80.54) | 0.450 |
| Age at First Birth, n (%) | 0.213 | |||
| Nulliparious | 81 (20.88) | 45 (22.17) | 36 (19.84) | |
| < 25 years | 163 (42.01) | 77 (37.93) | 86 (45.24) | |
| ≥ 25 years | 143 (36.86) | 81 (39.90) | 62 (34.92) | |
| Oral Contraceptive use, n (%) | 214 (55.15) | 111 (54.68) | 103 (55.68) | 0.844 |
| Menopausal and HRT3 status, n (%) | 0.515 | |||
| Premenopausal | 88 (22.86) | 43 (21.29) | 45 (24.59) | |
| Postmenopausal and no HRT use | 164 (42.60) | 83 (41.09) | 81 (44.26) | |
| Postmenopausal and with HRT use | 133 (34.55) | 76 (37.62) | 57 (31.15) | |
| Family History of Ovarian Cancer, n (%) | 28 (7.22) | 15 (7.39) | 13 (7.03) | 0.891 |
| Smoking history, n (%) | 0.664 | |||
| Never | 178 (45.88) | 90 (44.33) | 88 (47.57) | |
| Former | 181 (46.65) | 99 (48.77) | 82 (4432) | |
| Current | 29 (7.47) | 14 (6.90) | 15 (8.11) |
1
Post-diagnosis BMI self-reported on average within the first year post-diagnosis.
2
Surveillance Epidemiology and End Results (SEER)
3
Hormone Replacement Therapy (HRT)