Table 2.
BMI at three time points and risk of ovarian cancer mortality in women diagnosed with ovarian cancer (N=388).
| Multivariable-Adjusted Model1 |
||||
|---|---|---|---|---|
| Events / Cases | HR | 95% CI | P-value/ P for trend | |
| BMI during 20s | ||||
| Continuous | 144/382 | 1.06 | (1.01, 1.12) | 0.013 |
| BMI Dichotomized | ||||
| BMI < 25 | 131/351 | 1.00 | ||
| BMI ≥ 25 | 13/31 | 1.82 | (1.02, 3.27) | 0.045 |
| BMI 5 yrs prior2 | ||||
| Continuous | 145/381 | 1.03 | (1.01, 1.06) | 0.020 |
| BMI Dichotomized | ||||
| BMI < 25 | 72/205 | 1.00 | ||
| BMI ≥ 25 | 73/176 | 1.30 | (0.92, 1.83) | 0.135 |
| Post-diagnosis BMI3 | ||||
| Continuous | 146/388 | 1.03 | (1.00, 1.06) | 0.054 |
| BMI Dichotomized | ||||
| BMI < 25 | 76/203 | 1.00 | ||
| BMI ≥ 25 | 70/185 | 1.05 | (0.75, 1.48) | 0.782 |
1
Adjusted for age, stage, histology, education, oral contraceptive use, menopausal status and HRT use, parity, age at first birth, family history of ovarian cancer and time from ovarian cancer diagnosis to study enrollment
2
Self reported BMI of 5 years prior to diagnosis
3
Denotes the post-diagnosis self-reported BMI by the study participants when the study questionnaire was completed (approximately 9 months after diagnosis)