TABLE 3.
Influence of ompX expression on tolerance to SDS and antibiotic compounds
| Strain | Relevant genotype | % Survival in the presence of SDS (0.4%)a | Radius of inhibition zone (mm) in the presence of:
|
|||||
|---|---|---|---|---|---|---|---|---|
| Amikacin (30 μg) | Cephalosporin (30 μg) | Gentamicin (10 μg) | Novobiocin (30 μg) | Nalidixic acid (30 μg) | Compound sulfonamides (300 μg) | |||
| PC31 | Wild type | 43 ± 19 | 8.9 ± 0.2 | 4.4 ± 0.2 | 8.0 ± 0.6 | 3.8 ± 0.2 | 9.5 ± 0.6 | 6.4 ± 0.7 |
| KO3 | ΔompX::cam | 70 ± 14 | 5.3 ± 0.7 | 1.1 ± 0.2 | 4.8 ± 0.6 | 0 | 3.3 ± 0.5 | 0 |
| MS7 | fim::kan | 22 ± 6 | 8.3 ± 0.7 | 4.2 ± 0.3 | 8.0 ± 1.0 | 3.8 ± 0.3 | 9.2 ± 0.6 | 5.6 ± 0.2 |
| KO6 | ΔompX::cam fim::kan | 62 ± 5 | 6.5 ± 0.3 | 1.1 ± 0.2 | 4.7 ± 0.4 | 0 | 3.4 ± 0.6 | 0.2 ± 0.2 |
a
The viability of cells was determined by determining the numbers of CFU per milliliter before and after 5 min of exposure to SDS.