TABLE 1.

Highly represented subrole families

Main role	Subrole	Subrole IDa	No. identified	Total no.	%
Protein synthesis	Ribosomal proteins: synthesis and modification	158	46	62	74.19
Protein synthesis	tRNA aminoacylation	137	24	33	72.73
Protein synthesis	Translation factors	169	8	12	66.67
Cellular processes	Adaptations to atypical conditions	149	10	18	55.56
Energy metabolism	Glycolysis and gluconeogenesis	116	17	31	54.84
Purines, pyrimidines, nucleosides, and nucleotides	Purine ribonucleotide biosynthesis	125	8	15	53.33
Energy metabolism	ATP-proton motive force interconversion	111	6	12	50.00
Protein fate	Protein folding and stabilization	95	11	22	50.00
Energy metabolism	TCA cycle	120	10	21	47.62
Cellular processes	Detoxification	96	10	22	45.45

^aID, the identification number assigned in the current genome annotation to a given subrole.