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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Oct 21;31(1):50–57. doi: 10.1161/ATVBAHA.110.210971

Figure 2.

Figure 2

TLR4 and TLR2 deficiency reduce early intimal lipid accumulation in the LCAA of younger ApoE KO mice fed either chow (20 week-old female), or Western diet for 3 weeks before lesion analysis (18 week-old male). Representative Oil Red O-stained aortic arch segments from mice of the indicated genotypes and diet are shown in A. Charts in B show % of LCAA surface area staining positively for neutral lipid. Number of mice per group (chow and Western diet): ApoE (10 and 8), TLR2 DKO (12 and 12), and TLR4 DKO (6 and 8). **P < 0.01 vs. ApoE KO.