Figure 3.

Phylogenetic analyses and genomic organization of Calumenin orthologs found in deuterostome genomes. (A) Phylogeny of the predicted proteins encoded by the duplicate Calumenin genes found in Oikopleura. The tree was constructed based upon neighbor-joining analyses and rooted using Reticulocalbin. Statistical support values ≥80% obtained with different methods are included over conserved nodes, as described in Figure. 2. Abbreviations are as in Figure. 2. (B) Schematic depictions of the genomic regions encompassing Calumenin paralogs in Ciona intestinalis, Ciona savignyi, Oikopleura dioica and Strongylocentrotus purpuratus. The names of the genes flanking the Calumenin genes are either those indicated in the genome browsers of the respective species or those identified using the reciprocal best BLAST hit method.