Table 2.

Effect of HFD, HSD and Garcinia treatments on blood glucose, G6pD and adipose tissues during three months in different groups of rats

	Control	HFD	HFD+G	HSD	HSD+G
Glucose (mg/dl)	59.0 ± 1.6 a	111.0 ± 4.1b	91.0 ± 3.9c	71.0 ± 3.2 ad	63.0 ± 3.6 ad
G6pD (mU/ml)	0.25 ± 0.02a	0.14 ± 0.01b	0.12 ± 0.002b	0.53 ± 0.04c	0.54 ± 0.03 c
Mesenteric fat (g)	1.7 ± 0.19a	3.6 ± 0.41b	2.6 ± 0.29c	3. 2 ± 0.29c	2.2 ± 0.33 e
Perirenal fat (g)	2.4 ± 0.29a	3.3 ± 0.23b	1.3 ± 0.31ac	3.4 ± 0.2bc	2.2 ± 0.3d
Epididymal fat (g)	0.88 ± 0.06a	2.3 ± 0.075b	1.1 ± 0.041c	1.9 ± 0.025b	1.2 ± 0.1dc

Each value is the mean ± SEM. Means have different superscript letters indicate significant variation at (P ≤ 0.05), while the same letters indicate non significant variation

Plasma glucose was significant increased in HFD group compared with control and these levels were significantly lowered in HFD+G than HFD group p ≤ 0.05. There were significant increases in G6pD activities in HSD and HSD+G groups p ≤ 0.05 than control, while giving Garcinia ameliorated these changes.

Mesenteric, perirenal and epididymal adipose tissue weight were significantly increased in HFD and HSD compared with control group.

The mesenteric, perirenal and epididymal fat-pad weights were reduced by 28%, 61% and 52% respectively in rats fed HFD+G than HFD rat (p < 0.05). While the mesenteric, perirenal and epididymal fat-pad weights were reduced by 31%, 35% and 37% respectively, in rats fed HSD+G than HSD rat. Garcinia treatment tended to decrease adipose tissues weight compared with HFD and HSD

Effect of HFD, HSD and Garcinia treatments on renal catalase and both serum and renal MDA and NO levels in rats.