Table 2.
Sp1 sites in demethylated tumour suppressor gene promoters
RARB | CST6 | CCND2 | CDKN2A | |
---|---|---|---|---|
Number of demethylated CGs | 8-13 | 1-8, 14-18, 25, 31 | 1-7, 21-28 | 1-9, 19-28 |
Number of demethylated CGs containing Sp1 sites | 12 | 5, 12, 13 | 1, 2 | 9, 10, 22 |
Putative transcription factors binding sites contained in demethylated CGs | NF-kappaB, c-Re1 | GATA-1, Ahr/Arnt | CREB, MYC, USF1, MAX, SRY, MZF-1 | USF1, MZF-1, CP2 |
Putative transcription factor binding sites as determined by TFSEARCH http://www.cbrc.jp/research/db/TFSEARCH.html.