Table 1. PKCδ overexpression is accompanied by DNA damage.

		SH-SY-5Y		SK-N-BE-2C
		Standard (A.U.)	fpg (A.U.)	Standard (A.U.)	fpg (A.U.)
CTR	EV	0.0006±0.0001	0.0004±0.0001	0.0008±0.0001	0.0006±0.0001
	PKCδ	0.0006±0.0001	12.111±4.632**,°°	0.0009±0.0001	7.321±1.632**,°°
BSO	EV	0.0005±0.0001	0.0005±0.0001	10.532±1.326**	12.569±1.315**
	PKCδ	20.4718±3.9458§§	17.5194±3.9908§§	20.4718±3.9458§	17.5194±3.9908§
DPI	EV	0.0004±0.0001	0.0007±0.0002	0.0008±0.0002	0.0007±0.0004
	PKCδ	0.0006±0.0001	0.0004±0.0001••	0.0009±0.0002	0.0007±0.0002••
DPI+BSO	EV	0.0003±0.0001	0.0005±0.0001	0.0004±0.0001§§	0.0004±0.0001§§
	PKCδ	0.0005±0.0001◊◊	0.0004±0.0001◊◊	0.0006±0.0001◊◊	0.0005±0.0001◊◊

NB cells, transiently transfected with empty vector (EV) or PKCδ plasmid, were treated with 1 mM BSO for 24 h. Where indicated, cells were pre-treated with 25 nM DPI for 30 min. DNA fragmentation (standard) and oxidation (fpg) were evaluated by comet test. The reported values derive from tail moment analyses.

**p<0.01 vs EV CTR/fpg;

°°p<0.01 vs PKCδ CTR standard;

^§ p<0.05 vs EV + BSO;

^§§ p<0.01 vs EV + BSO;

^•• p<0.01 vs PKCδ CTR fpg;

^◊◊ p<0.01 vs PKCδ+BSO.