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. Author manuscript; available in PMC: 2012 Feb 11.
Published in final edited form as: Vaccine. 2010 Dec 31;29(8):1666–1676. doi: 10.1016/j.vaccine.2010.12.036

Figure 7. CD8 T cells reduce viral loads in the lung.

Figure 7

Naïve mice were challenged with 0.1 LD50 of VACV-WR by the i.n. route following adoptive transfer of PBS, CD8 T cells or immune sera from NYCBH mice as described in Materials and Methods. Data shown are PFU/gm of lung tissue four days following challenge in mice that received PBS (open circles, n=12), CD8 T cells (open squares, n=8) or immune sera (open triangles, n=6) prior to challenge. Each symbol represents viral titers obtained in lungs of individual mice; mean values are denoted by horizontal lines. p values <0.05 were considered to be significant.