Figure 1.

Body weight and diet-induced metabolic changes in mice. (a) Weight gain in CD-fed, HFD-fed or ob/ob mice as indicated. (b) CD-fed, HFD-fed and ob/ob mice were starved for 16 h. Basal blood glucose levels (left panel) and blood glucose levels (60 min) during an OGT (right panel) were determined. (c) CD-fed, HFD-fed and ob/ob mice were starved for 16 h. Serum insulin (left panel) and leptin (right panel) were determined. **P < .01; *P < .05 versus CD-fed mice. Bars indicate the mean ± SD obtained from 26 individual animals.