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. 2011 Jan 20;2010:476969. doi: 10.1155/2010/476969

Figure 7.

Figure 7

Myofibroblasts at the wound site. (a) Expression of α-SMA mRNA in nonwounded back skin and wound tissue isolated from CD-fed, HFD-fed or ob/ob mice. The time after injury is indicated. *P < .05 as indicated by the bracket. Each single experimental time point depicts the mean ± SD obtained from 12 wounds (n = 12) isolated from 4 individual animals (n = 4). (b) Immunoblots showing the presence of α-SMA protein in nonwounded (ctrl) and wounded (3 to 11 d wd) skin in CD, HFD and ob/ob mice as indicated. Each time point depicts 8 wounds (n = 8) from 4 individual mice (n = 4). A Ponceau S (PonS) staining of the immunoblots is shown to control equal loading. (c) Sections from 7-day wound tissue isolated from CD and HFD mice were stained for α-SMA protein as indicated (red colour). The epithelial margins are indicated by a yellow line. Scale bar = 500 μm. gt, granulation tissue; ne, neoepithelium; sc, scab; we, wound margin epithelia.