Figure 4.

Visualization of amyloid fibrils formed on cell membranes using TIRFM. SH-SY5Y cells were treated with 50 μM Aβ-(1–40) ((a), (b)) or 5 μM Aβ-(1–42) ((c), (d)) for 48 h. Amyloid fibrils were stained with 20 μM Congo red. (a) and (c) are DIC images, while (b) and (d) are TIRF images. Data taken from [17].