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. 2011 Jan 13;2011:956104. doi: 10.4061/2011/956104

Table 1.

Parameters for the binding of DAC-Aβs to GM1/cholesterol/SM (1 : 1 : 1) LUVs at 37°C.

Aβ K (106 M−1)a xmaxb(Aβ/GM1, mol/mol) Ref.
DAC-Aβ-(1–42) 11.1 ± 2.4 0.0361 ± 0.0021 [17]
DAC-Aβ-(1–40) 8.6 ± 3.6 0.0313 ± 0.0041 [16]
DAC-Aβ-(1–28) 0.0184 ± 0.0007 0.0313c [16]

aBinding constant.

bMaximal value of x (bound Aβ per exofacial GM1, mol/mol).

cAssumed to be the same as that of DAC-Aβ-(1–40).