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Morphometric assessment of atherosclerotic lesions in Apoe−/−Apob100/100 (n = 44), Apoe−/−Apob+/+ (n = 40), Ldlr−/−Apob100/100 (n = 42), and Ldlr−/−Apob+/+ (n = 40) mice. Differences between all groups were significant at the P < 0.0001 level with one exception: the lesions in Apoe−/−Apob+/+ mice were different from those in Apoe−/−Apob100/100 mice at P = 0.0004. Reproduced from a paper by Véniant et al. (25) with permission from the American Society of Clinical Investigation.
