Table 3.
Clinical, morphologic, and cytogenetic characteristics of patients with acute myeloid leukemia and isolated trisomy 14.
| Age (Y) | Sex | WBC (109/L) | Hb (g/dL) | Platelet (109/L) | WHO classification | Karyotype | Cellularity (%) | Blast (%) | Trilineage dysplasia |
|---|---|---|---|---|---|---|---|---|---|
| 70 | M | 4.3 | 10.3 | 56 | AML with maturation | 47, XY, i(14)(q10) [2]/46, XY [17]* | 55 | 26 | Yes |
| 61 | M | 162 | 8.1 | 63 | AML with maturation | 47, XY, +14 [16] | 95 | 60 | Yes |
| 57 | M | 1.1 | 9.7 | 59 | AML without maturation | 47, XY, +14 [2]/46, XY [17]* | 25 | 50 | Yes |
| 65 | M | 2.1 | 10.1 | 305 | AML with maturation | 47, XY, +14 [16] | 85 | 37 | Yes |
*Abnormal clone confirmed by FISH.
Y: years; M: male; F: female; WBC: white blood cell; Hb: hemoglobin.