. Author manuscript; available in PMC: 2011 Feb 8.

Published in final edited form as: Depress Anxiety. 2009;26(11):1004–1011. doi: 10.1002/da.20611

Table 2.

Probandwise odds ratios for monozygotic and dizygotic twins of column diagnosis if twin has row diagnosis adjusted for sex and age.

Monozygotic twins

	PD^a	AG^a	PDorAG^a	PD&AG^a	PDNoAG^a	AGnoPD^a	MD^a	SP^b
PD	5.8 (3.5; 9.6)
AG	5.1 (2.9; 8.9)	10.3 (6.3; 16.8)
PDorAG	5.9 (3.8; 9.1)	8.1 (5.2; 12.4)	7.7 (5.4; 11.0)
PD&AG	5.3 (2.3; 12.0)	7.2 (3.3; 15.9)	6.0 (3.0; 12.0)	8.4 (2.9; 24.5)
PDNoAG	5.5 (3.0; 10.2)	3.6 (1.7; 7.6)	5.3 (3.1; 9.1)	3.2 (1.0; 10.4)	6.5 (3.2; 13.0)
AGnoPD	5.0 (2.4; 10.4)	11.1 (6.0; 20.4)	9.1 (5.2; 15.7)	6.0 (2.1; 17.3)	4.0 (1.6; 10.3)	12.8 (6.2; 26.6)
MD	2.8 (2.0; 4.0)	2.6 (1.8; 3.8)	2.7 (2.0; 3.5)	3.7 (2.1; 6.5)	2.4 (1.6; 3.7)	2.2 (1.4; 3.7)	2.9 (2.5; 3.3)
SP	3.6 (1.5; 8.8)	6.5 (3.1; 13.9)	5.6 (2.9; 10.8)	4.0 (0.9; 17.5)	3.3 (1.1; 9.4)	6.6 (2.7; 16.2)	2.6 (1.5; 4.5)	11.9 (3.7; 38.8)

Dizygotic twins

PD	3.6 (1.7; 6.6)
AG	1.1 (0.4; 2.9)	4.6 (2.5; 7.5)
PDorAG	2.7 (1.4; 4.4)	3.3 (1.9; 5.2)	3.5 (2.2; 5.0)
PD&AG	0.9 (0.1; 6.3)	1.6 (0.4; 6.5)	1.6 (0.5; 5.1)	0.0 (0.0; Inf)
PDNoAG	5.2 (2.4; 9.9)	0.9 (0.2; 3.3)	3.2 (1.5; 5.8)	1.4 (0.2; 9.7)	7.5 (3.2; 14.7)
AGnoPD	1.4 (0.4; 4.0)	6.7 (3.5; 11.3)	4.6 (2.4; 7.5)	2.6 (0.6; 10.5)	0.7 (0.1; 4.5)	9.4 (4.5; 16.5)
MD	1.7 (1.2; 2.5)	1.4 (1.0; 2.0)	1.6 (1.3; 2.2)	1.3 (0.7; 2.4)	1.9 (1.3; 3.2)	1.5 (1.0; 2.4)	1.5 (1.3; 1.7)
SP	2.9 (1.1; 7.4)	1.8 (0.6; 5.0)	2.1 (0.9; 4.7)	3.6 (0.8; 15.4)	2.5 (0.7; 8.1)	1.2 (0.3; 5.1)	1.5 (0.8; 2.6)	1.5 (0.2; 11.0)

Note. PD = Panic disorder; AG = Agoraphobia; PDorAG = Panic or agoraphobia; PD&AG = Panic with agoraphobia; PDnoAG = Panic without agoraphobia; AGnoPD = Agoraphobia without panic; MD = Depression; SP = Social phobia.

N = 2495 monozygotic and 2945 dizygotic twin pairs.

N = 1337 monozygotic and 1384 dizygotic twin pairs.