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. Author manuscript; available in PMC: 2011 Feb 8.
Published in final edited form as: J Immunol. 2009 Dec 11;184(2):965–974. doi: 10.4049/jimmunol.0902840

Figure 7.

Figure 7

Vitamin D decreases RSV induction of NF-κB-linked chemokines and cytokines in airway epithelium while maintaining the antiviral state. Respiratory epithelium recognizes viruses via pattern recognition receptors. Ligand engagement results in activation of NF-κB and NF-κB linked genes including IFNβ and chemokines. Vitamin D modulates the airway epithelial responses to RSV by inhibiting NF-κB signaling. In spite of dampening the innate antiviral response, vitamin D does not jeopardize viral clearance.