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. 2011 Jan 11;87(1):1–12. doi: 10.2183/pjab.87.1

Table 4.

Comparison of biological activities of the purified mutant VT1s and wild-type VT1 (from Ref. 38)

Toxin Cytotoxic
activity
CD50 (µg)
Mouse
lethality
LD50 (µg)
Inhibition of
protein synthesis
ED50 (µg)
E167Q 30 80 >100
R170L 9 10 2
Wild-type 0.0001 0.04 0.008