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. Author manuscript; available in PMC: 2012 Feb 5.
Published in final edited form as: Virology. 2010 Dec 4;410(1):234–239. doi: 10.1016/j.virol.2010.11.011

Figure 5. Editing of XMRV proviruses derived from virions produced by 22RV1 and 22RV1/hA3G cells.

Figure 5

XMRV virions derived from the parental 22RV1 cell line (A) or from 22RV1 cells engineered to express hA3G (B), as described in Fig. 4A, were used to infect wildtype LNCaP cells. At 48 h post-infection, total DNA was harvested and a 450 bp segment of the XMRV gag gene isolated by PCR and cloned. Twenty-two clones were then sequenced from each infection (9,900 bp x 2) to reveal the mutations described in this figure.